Purification of Robust L-Asparaginase from Capsicum annum and its Therapeutic Efficacy in Leukemia
نویسندگان
چکیده
منابع مشابه
Antioxidant Potential of Bell Pepper (Capsicum annum L
The interests in the consumption of pepper fruits (Capsicum annum L.) is, to a large extent due to its content of bioactive compounds and their importance as dietary antioxidants. Peppers are used as a colourant, flavourant, and/or as a source of pungency. Peppers can be used fresh, dried, fermented, or as an oleoresin extract. It has both nutritional and nutraceutical importance. It contains a...
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L- asparaginase enzyme is a renown enzyme due to its chemotherapeutic properties. This enzyme could also be employed in food processing technology. The present study aimed, optimizing the agitation and aeration rate in L-asparaginase production, using Candida utilis, ATCC 9950 in batch fermentation system. Beet molasses used as the carbohydrate source for enzyme production. A maximum asparagina...
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L-asparaginase is an anti-neoplastic agent used in the lymphoblastic leukaemia chemotherapy. In the present study a novel strain, Streptomyces gulbargensis was explored for the production of extra-cellular L-asparaginase using groundnut cake extract. The optimum pH, temperature, inoculum size and agitation speed for enzyme production were pH 8.5, 40°C, 1x10(8)spores/ml and 200 rev/min respectiv...
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The purification and properties of a tumor inhibitory l-asparaginase from Serratia marcescens are described. The following properties of the enzyme were examined: kinetics of the enzyme reaction, catalytic activity as a function of pH, boundary sedimentation velocity, electrophoresis on polyacrylamide gel, immuno-electrophoresis against homologous and heterologous antisera, immunodiffusion, blo...
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ژورنال
عنوان ژورنال: Pakistan Veterinary Journal
سال: 2019
ISSN: 0253-8318,2074-7764
DOI: 10.29261/pakvetj/2019.048